A study design in which one or more groups of individuals who are free of a particular disease of interest are monitored over time, during which some of them develop the disease. Certain characteristics of all individuals, known as exposure variables, are monitored at the beginning of the study and again at each follow-up, in order to determine whether particular exposures are risk-factors for developing the disease.
Friis, R. H. and T.A. Sellers. 2004. Epidemiology for Public Health Practice, Sudbury, MA: Jones and Bartlett Publishers.
Rosner, B.. 2006. Fundamentals of Biostatistics, 6th ed., Belmont, CA: Duxbury Press.
Prospective Evaluation Synthesis, 1990.
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